How Does Phentermine Work? Learn Pros & Cons Of Phentermine For Weight Loss

Phentermine, like many other prescription drugs, works with chemicals called neurotransmitters in your brain. It actually stimulates your neuron bundles to release a particular group of neurotransmitters known as catecholamines, these include dopamine, epinephrine (formally known as adrenalin), and norepinephrine (noradrenalin).
These neurotransmitters signal a fight or flight response in your body which, in turn, puts a halt to the hunger signal. As a result, you lose your appetite because your brain doesn't receive the hunger message.
This drop in appetite is perhaps due to phentermine's affects on leptin levels in the brain. It is theorized that phentermine can raise levels of leptin which signal satiety. It is also theorized that increased levels of the catecholamines are partially responsible for halting another chemical messenger know as neuropeptide Y. This chemical initiates eating, decreases energy expenditure, and increases fat storage.